Coffee - How Does It Work?

The extent I think about coffee is pretty much limited to me thinking that one person goes from hateful to loving in about 25 minutes. Not much more than that. Sometimes when I'm feeling like going deeper than "I want to wake up" or "Chevron or Starbucks?", I am curious to know how it works physiologically. Well, here's some information from How Stuff Works:

Why do so many people consume so much caffeine? Why does caffeine wake you up? By understanding the drug's actions inside the body you can see why people use it so much. In the HowStuffWorks article How Sleep Works, the action of adenosine is discussed. As adenosine is created in the brain, it binds to adenosine receptors. The binding of adenosine causes drowsiness by slowing down nerve cell activity. In the brain, adenosine binding also causes blood vessels to dilate (presumably to let more oxygen in during sleep).

To a nerve cell, caffeine looks like adenosine. Caffeine therefore binds to the adenosine receptor. However, it doesn't slow down the cell's activity like adenosine would. So the cell cannot "see" adenosine anymore because caffeine is taking up all the receptors adenosine binds to. So instead of slowing down because of the adenosine level, the cells speed up. You can see that caffeine also causes the brain's blood vessels to constrict, because it blocks adenosine's ability to open them up. This effect is why some headache medicines like Anacin contain caffeine -- if you have a vascular headache, the caffeine will close down the blood vessels and relieve it.

So now you have increased neuron firing in the brain. The pituitary gland sees all of the activity and thinks some sort of emergency must be occurring, so it releases hormones that tell the adrenal glands to produce adrenaline (epinephrine). Adrenaline is the "fight or flight" hormone, and it has a number of effects on your body:

• Your pupils dilate.
• Your breathing tubes open up (this is why people suffering from severe asthma attacks are sometimes injected with epinephrine).
• Your heart beats faster.
• Blood vessels on the surface constrict to slow blood flow from cuts and also to increase blood flow to muscles. Blood pressure rises.
• Blood flow to the stomach slows.
• The liver releases sugar into the bloodstream for extra energy.
• Muscles tighten up, ready for action.
• You feel like going to the mall. (ok, I added that one) 

This explains why, after consuming a big cup of coffee, your hands get cold, your muscles tense up, you feel excited and you can feel your heart beat increasing. And for some people, those very feelings are mimicked when stepping into the line at Starbucks. The next time you want sex and your partner doesn't because they have a headache, quickly produce a cup of brew and you might just get some, or find out they just aren't into you.